True 99th centile of high sensitivity cardiac troponin for hospital patients: prospective, observational cohort study.

ABSTRACT:

Objective

To determine the distribution, and specifically the true 99th centile, of high sensitivity cardiac troponin I (hs-cTnI) for a whole hospital population by applying the hs-cTnI assay currently used routinely at a large teaching hospital.

Design

Prospective, observational cohort study.

Setting

University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom, between 29 June 2017 and 24 August 2017.

Participants

20 000 consecutive inpatients and outpatients undergoing blood tests for any clinical reason. Hs-cTnI concentrations were measured in all study participants and nested for analysis except when the supervising doctor had requested hs-cTnI for clinical reasons.

Main outcome measures

Distribution of hs-cTnI concentrations of

SUBMITTER: Mariathas M 

PROVIDER: S-EPMC6415647 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature