Beyond dichotomy: patterns and amplitudes of SSEPs and neurological outcomes after cardiac arrest.

ABSTRACT:

Background

We hypothesized that the absence of P25 and the N20-P25 amplitude in somatosensory evoked potentials (SSEPs) have higher sensitivity than the absence of N20 for poor neurological outcomes, and we evaluated the ability of SSEPs to predict long-term outcomes using pattern and amplitude analyses.

Methods

Using prospectively collected therapeutic hypothermia registry data, we evaluated whether cortical SSEPs contained a negative or positive short-latency wave (N20 or P25). The N20-P25 amplitude was defined as the largest difference in amplitude between the N20 and P25 peaks. A good or poor outcome was defined as a Glasgow-Pittsburgh Cerebral Performance Category (CPC) score of 1-2 or 3-5, respectively, 6 months after cardiac arrest.

Results

A total of 192 SSEP

SUBMITTER: Oh SH 

PROVIDER: S-EPMC6582536 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature