Multimorbidity Burden and Adverse Outcomes in a Community-Based Cohort of Adults with Heart Failure.

ABSTRACT:

Objectives

To assess multimorbidity burden and its association with clinical outcomes in adults with heart failure (HF) according to sex, age, and HF type.

Design

Retrospective cohort study.

Setting

Five healthcare delivery systems across the United States.

Participants

Adults with HF (N=114,553).

Measurements

We characterized participants with respect to the presence of 26 chronic conditions categorized into quartiles based on overall burden of comorbidity (<5, 5-6, 7-8, ≥9). Outcomes included all-cause death and hospitalization for HF or any cause. Multivariable Cox regression was used to evaluate the adjusted association between categorized burden of multimorbidity burden and outcomes.

Results

Individuals with more morbidities were more likely

SUBMITTER: Tisminetzky M 

PROVIDER: S-EPMC6697073 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature