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Reduced oxygen concentration during human IVF culture improves embryo utilization and cumulative pregnancy rates per cycle.


ABSTRACT:

SUBMITTER: Van Montfoort APA 

PROVIDER: S-EPMC6975868 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Reduced oxygen concentration during human IVF culture improves embryo utilization and cumulative pregnancy rates per cycle.

Van Montfoort Aafke P A APA   Arts Eus G J M EGJM   Wijnandts Lydia L   Sluijmer Alexander A   Pelinck Marie-José MJ   Land Jolande A JA   Van Echten-Arends Jannie J  

Human reproduction open 20200122 1


<h4>Study question</h4>Do different oxygen levels during human IVF embryo culture affect embryo utilization, cumulative IVF success rates per cycle and neonatal birthweight?<h4>Summary answer</h4>After 2 days of culture, a lower oxygen level (5%) leads to more good-quality embryos and more embryos that can be cryopreserved, and thereby to a higher cumulative live birth rate per cycle when compared to embryo culture in 20% oxygen, while birthweights are similar.<h4>What is known already</h4>Sever  ...[more]

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