Well Water and Parkinson's Disease in Medicare Beneficiaries: A Nationwide Case-Control Study.

ABSTRACT:

Background

Well water frequently is considered a risk factor for Parkinson's disease (PD), but few studies were designed appropriately to test whether geographic factors affect PD risk.

Objective

To determine the risk of PD in relation to residential use of private well water.

Methods

In a nationwide, population-based case-control study, we identified all incident PD cases (N = 89,790) and all comparable controls (N = 21,549,400) age 66-90 who solely relied on Medicare coverage in the U.S. in 2009. We estimated the probability of use of private well water using zip code of residence at diagnosis/reference and U.S. Census data on household water source. We modeled this exposure linearly in logistic regression to calculate the odds ratio (OR) and 95% confidence interval

SUBMITTER: Silver MR 

PROVIDER: S-EPMC7342021 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature