The National COVID Cohort Collaborative (N3C): Rationale, design, infrastructure, and deployment.

ABSTRACT:

Objective

Coronavirus disease 2019 (COVID-19) poses societal challenges that require expeditious data and knowledge sharing. Though organizational clinical data are abundant, these are largely inaccessible to outside researchers. Statistical, machine learning, and causal analyses are most successful with large-scale data beyond what is available in any given organization. Here, we introduce the National COVID Cohort Collaborative (N3C), an open science community focused on analyzing patient-level data from many centers.

Materials and methods

The Clinical and Translational Science Award Program and scientific community created N3C to overcome technical, regulatory, policy, and governance barriers to sharing and harmonizing individual-level clinical data. We developed solution

SUBMITTER: Haendel MA 

PROVIDER: S-EPMC7454687 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature