Programmed Adult Kidney Disease: Importance of Fetal Environment.
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ABSTRACT:
SUBMITTER: Argeri R
PROVIDER: S-EPMC7546361 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Programmed Adult Kidney Disease: Importance of Fetal Environment.
Argeri Rogério R Thomazini Fernanda F Lichtenecker Débora Conte Kimura DCK Thieme Karina K do Carmo Franco Maria M Gomes Guiomar Nascimento GN
Frontiers in physiology 20200925
The Barker hypothesis strongly supported the influence of fetal environment on the development of chronic diseases in later life. Multiple experimental and human studies have identified that the deleterious effect of fetal programming commonly leads to alterations in renal development. The interplay between environmental insults and fetal genome can induce epigenetic changes and lead to alterations in the expression of renal phenotype. In this review, we have explored the renal development and i ...[more]
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