Echocardiographic surrogate of left ventricular stroke work in a model of brain stem death donors.

ABSTRACT:

Background

The commonest echocardiographic measurement, left ventricular ejection fraction, can not necessarily predict mortality of recipients following heart transplantation potentially due to afterload dependency. Afterload-independent left ventricular stroke work index (LVSWI) is alternatively recommended by the current guideline; however, pulmonary artery catheters are rarely inserted in organ donors in most jurisdictions. We propose a novel non-invasive echocardiographic parameter, Pressure-Strain Product (PSP), as a potential surrogate of catheter-based LVSWI. This study aimed to investigate if PSP could correlate with catheter-based LVSWI in an ovine model of brain stem death (BSD) donors. The association between PSP and myocardial mitochondrial function in the post-transpl

SUBMITTER: Sato K 

PROVIDER: S-EPMC7616761 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature