MADA: a web service for analysing DNA methylation array data.

ABSTRACT:

Background

DNA methylation in the human genome is acknowledged to be widely associated with biological processes and complex diseases. The Illumina Infinium methylation arrays have been approved as one of the most efficient and universal technologies to investigate the whole genome changes of methylation patterns. As methylation arrays may still be the dominant method for detecting methylation in the anticipated future, it is crucial to develop a reliable workflow to analysis methylation array data.

Results

In this study, we develop a web service MADA for the whole process of methylation arrays data analysis, which includes the steps of a comprehensive differential methylation analysis pipeline: pre-processing (data loading, quality control, data filtering, and normalization

SUBMITTER: Hu X 

PROVIDER: S-EPMC7672854 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature