Dataset Information

Association of transferrin G258A and transferrin receptor A82G polymorphisms with the risk of Parkinson disease in certain area.

ABSTRACT:

Background

It has been reported that polymorphisms of transferrin (TF) G258A and transferrin receptor (TFR) A82G might be associated with susceptibility to Parkinson disease (PD).

Objective

Owing to limitation of sample size and inconclusive results, we conducted a meta-analysis to clarify the association.

Methods

By searching PubMed, Embase, Chinese National Knowledge Infrastructure, China Biological Medicine Database, and Wanfang Databases, the published articles about studies of the association of the TF G258A, TFR A82G gene polymorphisms with the risk of PD were collected. Q-statistics and I statistics were calculated to examine heterogeneity and summary odds ratios (ORs) and 95% confidence intervals (95%CI) were evaluated the association.