Diet quality, weight loss, and diabetes incidence in the Diabetes Prevention Program (DPP)

ABSTRACT:

Background

We evaluated whether diet quality is a predictor of weight loss and reduced diabetes risk, independent of caloric intake in the Diabetes Prevention Program (DPP) cohort, a randomized clinical trial of adults at risk for diabetes.

Methods

This secondary analysis included 2914 participants with available data (964 intensive lifestyle (ILS), 977 metformin, 973 placebo). Dietary intake was assessed using a 117-item food frequency questionnaire. Diet quality was quantified using the Alternative Healthy Eating Index 2010 (AHEI). AHEI ranges from 0 to 110, with higher scores corresponding to higher quality diets. ILS participants had greater improvement (p?Results An increase in AHEI score was associated with weight loss in ILS [? per 10-point increase (SE) -1.2?kg (0.3, p?Conclusions Controlling for weight, diet quality was not associated with diabetes incidence but helps achieve weight loss, an important factor in diabetes prevention.

Supplementary Information

The online version contains supplementary material available at 10.1186/s40795-020-00400-4.

SUBMITTER: Allaire B 

PROVIDER: S-EPMC7737274 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature