Dataset Information

Do not neglect SARS-CoV-2 hospitalization and fatality risks in the middle-aged adult population.

ABSTRACT:

Objectives

This study aimed at estimating the SARS-CoV-2 infection hospitalization (IHR) and infection fatality ratios (IFR) in France.

Patients and methods

A serosurvey was conducted in 9782 subjects from the two French regions with the highest incidence of COVID-19 during the first wave of the pandemic and coupled with surveillance data.

Results

IHR and IFR were 2.7% and 0.49% overall. Both were higher in men and increased exponentially with age. The relative risks of hospitalization and death were 2.1 (95% CI: 1.9-2.3) and 3.8 (2.4-4.2) per 10-year increase, meaning that IHR and IFR approximately doubled every 10 and 5 years, respectively. They were dramatically high in the very elderly (80-90 years: IHR: 26%, IFR: 9.2%), and also substantial in younger adults (40-50 years: IHR: 0.98%, IFR: 0.042%).

Conclusions

These findings support the need for comprehensive preventive measures to help reduce the spread of the virus, even in young or middle-aged adults.

SUBMITTER: Lapidus N

PROVIDER: S-EPMC7836556 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature

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Publications

Do not neglect SARS-CoV-2 hospitalization and fatality risks in the middle-aged adult population.

Lapidus Nathanael N Paireau Juliette J Levy-Bruhl Daniel D de Lamballerie Xavier X Severi Gianluca G Touvier Mathilde M Zins Marie M Cauchemez Simon S Carrat Fabrice F

Infectious diseases now 20210118 4

<h4>Objectives</h4>This study aimed at estimating the SARS-CoV-2 infection hospitalization (IHR) and infection fatality ratios (IFR) in France.<h4>Patients and methods</h4>A serosurvey was conducted in 9782 subjects from the two French regions with the highest incidence of COVID-19 during the first wave of the pandemic and coupled with surveillance data.<h4>Results</h4>IHR and IFR were 2.7% and 0.49% overall. Both were higher in men and increased exponentially with age. The relative risks of hos ...[more]

PMID: 33521775

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Dataset Information

Do not neglect SARS-CoV-2 hospitalization and fatality risks in the middle-aged adult population.

Objectives

Patients and methods

Results

Conclusions

Publications

Do not neglect SARS-CoV-2 hospitalization and fatality risks in the middle-aged adult population.

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