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Angiographic outcomes in STEMI patients receiving fibrinolysis with guideline directed optimal antithrombotic therapy.


ABSTRACT: STEMI is a major public health problem requiring timely reperfusion. Fibrinolysis remains prevalent reperfusion strategy where timely primary percutaneous coronary intervention (PCI) cannot be performed. Adjunctive antithrombotic agents are of utmost importance for maximizing the benefit of fibrinolysis. This prospective study evaluates the angiographic outcomes in STEMI patients receiving fibrinolysis with optimal antithrombotic therapy and reported TIMI 3 flow rates of 33.8% and 41.5% for streptokinase and reteplase respectively, that were significantly higher than various prior studies. This data reiterates the utility of thrombolysis in resource limited settings.

SUBMITTER: Durdana S 

PROVIDER: S-EPMC7961247 | biostudies-literature | 2021 Jan-Feb

REPOSITORIES: biostudies-literature

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Angiographic outcomes in STEMI patients receiving fibrinolysis with guideline directed optimal antithrombotic therapy.

Durdana Shazia S   Malik Mohammad Azharuddin MA   Hasan Asif A   Rabbani M U MU  

Indian heart journal 20201113 1


STEMI is a major public health problem requiring timely reperfusion. Fibrinolysis remains prevalent reperfusion strategy where timely primary percutaneous coronary intervention (PCI) cannot be performed. Adjunctive antithrombotic agents are of utmost importance for maximizing the benefit of fibrinolysis. This prospective study evaluates the angiographic outcomes in STEMI patients receiving fibrinolysis with optimal antithrombotic therapy and reported TIMI 3 flow rates of 33.8% and 41.5% for stre  ...[more]

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