Hematological predictors of mortality in neonates with fulminant necrotizing enterocolitis.

ABSTRACT:

Objective

Determine whether hematological and transfusion patterns following, the onset of NEC can identify infants likely to develop fulminant, fatal necrotizing enterocolitis (NEC).

Design

Determine hematological predictors of fulminant NEC.

Results

Of 336 neonates with NEC, 35 (10%) who developed fulminant NEC were born with higher birth weights and more frequently developed radiologically evident pneumoperitoneumand/or portal venous gas. Following the diagnosis of NEC, these infants were more likely to rapidly develop thrombocytopenia, lymphopenia, neutropenia, and lower total white blood cell counts compared to medical/surgical non-fulminant type. They were also more likely to have received a red blood cell (RBC) transfusion (76.7% vs. 53.1%, p = 0.001) within 48

SUBMITTER: Garg PM 

PROVIDER: S-EPMC7995678 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature