Can Inhibin B Reflect Ovarian Reserve of Healthy Reproductive Age Women Effectively?

ABSTRACT:

Objective

The reference range and potential value of inhibin B are still unclear and controversial. This study aimed to define the variation trend of inhibin B in healthy women with age and explore its value in the reflection of ovarian reserve.

Methods

A total of 2524 healthy reproductive age women from eight medical institutes nationwide were recruited. The variation tendency of inhibin B with age was primarily established in the first group of 948 women and validated in another 605. We evaluated the relationship between inhibin B and classic ovarian reserve and function markers. The potency of inhibin B in predicting AFC <5-7 was also estimated and compared with FSH.

Results

The nomogram showed that serum levels of inhibin B rapidly decreased after the age of 40. I

SUBMITTER: Wen J 

PROVIDER: S-EPMC8081350 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature