Association Between Depression and Clinical Outcomes in Patients With Hypertrophic Cardiomyopathy.

ABSTRACT: Background Hypertrophic cardiomyopathy (HCM) is considered to be the most common cause of sudden death in young people and is associated with an elevated risk of mood disorders. Depression has emerged as a critical risk factor for development and progression of coronary artery disease; however, the association between depression and HCM outcomes is less clear. We sought to examine the impact of depression on clinical outcomes in patients with HCM. Methods and Results Between January 2014 and December 2017, 820 patients with HCM were recruited and followed for an average of 4.2 years. End points were defined as sudden cardiac death (SCD) events and HCM-related heart failure events. A Chinese version of the Structured Clinical Interview followed the Diagnostic and Statistical Manual of Me

SUBMITTER: Hu HL 

PROVIDER: S-EPMC8174176 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature