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Fabrication of Thermochromic Membrane and Its Characteristics for Fever Detection.

ABSTRACT: Body temperature is an important indicator of the health status of the human body. Thus, numerous studies have been conducted in various fields to measure body temperature. In this study, a biocompatible thermochromic membrane that changes its color when the temperature becomes higher than the transition temperature for thermochromism was fabricated using an extrusion-based three-dimensional printing process. The printing material was prepared by mixing a thermochromic pigment and a thermoplastic polymer in various ratios. The effects of mixing ratio on the various properties of the fabricated membranes were experimentally investigated. It is presented that the fabricated lattice membrane had excellent thermochromic reaction, which was experimentally evaluated using a measurement of color brightness. The pigment content affected the diameter and surface morphology of the printed filament. The elastic modulus decreased, and thermochromic response became faster as the pigment concentration increased. Subsequently, a patch for fever detection was developed and then attached to the skin to demonstrate its color change according to body temperature. Results show that the fabricated thermochromic patch could be successfully applied to fever detection.

SUBMITTER: Jeon HS

PROVIDER: S-EPMC8269493 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature

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Fabrication of Thermochromic Membrane and Its Characteristics for Fever Detection.

Jeon Hyeon Seop HS Kim Jeong Hwa JH Jun Martin B G MBG Jeong Young Hun YH

Materials (Basel, Switzerland) 20210622 13

Body temperature is an important indicator of the health status of the human body. Thus, numerous studies have been conducted in various fields to measure body temperature. In this study, a biocompatible thermochromic membrane that changes its color when the temperature becomes higher than the transition temperature for thermochromism was fabricated using an extrusion-based three-dimensional printing process. The printing material was prepared by mixing a thermochromic pigment and a thermoplasti ...[more]

PMID: 34206427

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Project description:BackgroundThe regeneration of lost/damaged support tissue in the periodontium, including the alveolar bone, periodontal ligament, and cementum, is an ambitious purpose of periodontal regenerative therapy and might effectively reduce periodontitis-caused tooth loss. Guided tissue regeneration (GTR) is a technique currently used in dentistry for periodontal surgery, which allows osseous regeneration prior to soft tissue migration into the area of interest. Calcium phosphate-based bone grafts (mostly Tricalcium Phosphate or Hydroxyapatite) are bio ceramics that show the greatest similarity to the mineral found in the bone. Thereby, giving calcium-phosphate excellent biocompatibility, biodegradability and osteoconductivity. The aim of the study is to fabricate hydroxyapatite reinforced polymeric hydrogel membrane for regeneration.Materials and methodPure alginate fabrication was done by cross linking sodium alginate with calcium chloride. Hydroxyapatite (HAP) alginate (Alg) was formulated by adding nanoparticles to the alginate mixture, which was then cross-linked with calcium chloride to formulate a HAP alginate polymeric membrane. The Fourier-transform infrared spectroscopy (FT-IR), Scanning Electron Microscope (SEM), and biocompatibility tests were performed to analyse the membrane characteristics.ResultsFabricated Hydroxyapatite- alginate (Hap- Alg) membrane has longer durability, because of strong crystal structure which in turn might take a longer time to regenerate. The membrane was found to be biocompatible and HAp induces faster mineralisation which in turn will increase the tissue regeneration rate of the membrane.ConclusionThe findings of our study suggests that the HAP-Alg hydro gel membrane is highly durable and hemocompatible and it has faster mineralisation capability thus making it superior from the clinically available membranes for GTR. Further analyses needs to be conducted to evaluate the potential of this membrane to be used for regeneration.

Dataset Information

Fabrication of Thermochromic Membrane and Its Characteristics for Fever Detection.

Publications

Fabrication of Thermochromic Membrane and Its Characteristics for Fever Detection.

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