CBr₄ Mediated [4 + 1] Dehydrocyclization for the Synthesis of Functionalized Imidazo[1,5-a]heterocycles from Pyridin-2-ylmethanamines and Aldehydes.

ABSTRACT: A CBr₄ mediated [4 + 1] dehydrocyclization was developed for the synthesis of imidazo[1,5-a]heterocycles from pyridin-2-ylmethanamines and aldehydes. This method was highly practical with the advantages of wide substrate scope, functional group tolerance, and mild reaction conditions.

SUBMITTER: Wang Q 

PROVIDER: S-EPMC8358950 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature