Oxygen-enhanced functional lung imaging using a contemporary 0.55 T MRI system.

ABSTRACT: The purpose of this study was to evaluate oxygen-enhanced pulmonary imaging at 0.55 T with 3D stack-of-spirals ultrashort-T_E (UTE) acquisition. Oxygen-enhanced pulmonary MRI offers the measurement of regional lung ventilation and perfusion using inhaled oxygen as a contrast agent. Low-field MRI systems equipped with contemporary hardware can provide high-quality structural lung imaging by virtue of the prolonged T₂ *. Fortuitously, the T₁ relaxivity of oxygen increases at lower field strengths, which is expected to improve the sensitivity of oxygen-enhanced lung MRI. We implemented a breath-held T₁ -weighted 3D stack-of-spirals UTE acquisition with a 7 ms spiral-out readout. Measurement repeatability was assessed using five repetitions of oxygen-

SUBMITTER: Bhattacharya I 

PROVIDER: S-EPMC8377594 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature