Evaluation of Hepatic Iron Overload Using a Contemporary 0.55 T MRI System.

ABSTRACT:

Background

MRI T2* and R2* mapping have gained clinical acceptance for noninvasive assessment of iron overload. Lower field MRI may offer increased measurement dynamic range in patients with high iron concentration and may potentially increase MRI accessibility, but it is compromised by lower signal-to-noise ratio that reduces measurement precision.

Purpose

To characterize a high-performance 0.55 T MRI system for evaluating patients with liver iron overload.

Study type

Prospective.

Population

Forty patients with known or suspected iron overload (sickle cell anemia [n = 5], ß-thalassemia [n = 3], and hereditary spherocytosis [n = 2]) and a liver iron phantom.

Field strength/sequence

A breath-held multiecho gradient echo sequence at 0.55 T and 1.5 T.

As

SUBMITTER: Campbell-Washburn AE 

PROVIDER: S-EPMC9018883 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature