HIV Associated Preeclampsia: A Multifactorial Appraisal.
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ABSTRACT:
SUBMITTER: Naicker T
PROVIDER: S-EPMC8431090 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Publications
HIV Associated Preeclampsia: A Multifactorial Appraisal.
Naicker Thajasvarie T Govender Nalini N Abel Tashlen T Naidoo Nitalia N Moodley Merantha M Pillay Yazira Y Singh Shoohana S Khaliq Olive Pearl OP Moodley Jagidesa J
International journal of molecular sciences 20210825 17
<i>Introduction:</i> This review explores angiogenesis, vascular dysfunction, the complement system, RAAS, apoptosis and NETosis as potential pathways that are dysregulated during preeclampsia, HIV infection and ART usage. <i>Results:</i> HIV-1 accessory and matrix proteins are protagonists for the elevation of oxidative stress, apoptosis, angiogenesis, and elevation of adhesion markers. Despite the immunodeficiency during HIV-1 infection, HIV-1 exploits our cellular defence arsenal by escaping ...[more]
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