Ontology highlight
ABSTRACT:
SUBMITTER: Josyula A
PROVIDER: S-EPMC8459599 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Josyula Aditya A Omiadze Revaz R Parikh Kunal K Kanvinde Pranjali P Appell Matthew B MB Patel Pratikkumar P Saeed Hiwa H Sutar Yogesh Y Anders Nicole N He Ping P McDonnell Peter J PJ Hanes Justin J Date Abhijit A AA Ensign Laura M LM
Bioengineering & translational medicine 20210622 3
There are numerous barriers to achieving effective intraocular drug administration, including the mucus layer protecting the ocular surface. For this reason, antibiotic eye drops must be used multiple times per day to prevent and treat ocular infections. Frequent eye drop use is inconvenient for patients, and lack of adherence to prescribed dosing regimens limits treatment efficacy and contributes to antibiotic resistance. Here, we describe an ion-pairing approach used to create an insoluble mox ...[more]