Strain-level functional variation in the human gut microbiota based on bacterial binding to artificial food particles.
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ABSTRACT:
SUBMITTER: Patnode ML
PROVIDER: S-EPMC8529970 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Publications
Strain-level functional variation in the human gut microbiota based on bacterial binding to artificial food particles.
Patnode Michael L ML Guruge Janaki L JL Castillo Juan J JJ Couture Garret A GA Lombard Vincent V Terrapon Nicolas N Henrissat Bernard B Lebrilla Carlito B CB Gordon Jeffrey I JI
Cell host & microbe 20210210 4
Greater understanding of the spatial relationships between members of the human gut microbiota and available nutrients is needed to gain deeper insights about community dynamics and expressed functions. Therefore, we generated a panel of artificial food particles with each type composed of microscopic paramagnetic beads coated with a fluorescent barcode and one of 60 different dietary or host glycan preparations. Analysis of 160 Bacteroides and Parabacteroides strains disclosed diverse strain-sp ...[more]
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