Unknown

Dataset Information

0

Alterations in Neural Networks During Working Memory Encoding Related to Cognitive Impairment in Temporal Lobe Epilepsy.


ABSTRACT: Objective: The aim of the current study was to investigate the alterations in the neural networks of patients with temporal lobe epilepsy (TLE) during working memory (WM) encoding. Methods: Patients with TLE (n = 52) and healthy volunteers (n = 35) completed a WM task, during which 34-channel electroencephalogram signals were recorded. The neural networks during WM encoding were calculated in TLE patients with (TLE-WM) and without (TLE-N) WM deficits. Results: Functional connectivity strength decreased, and the theta network was altered in the TLE-WM group, although no significant differences in clinical features were observed between the TLE-N and TLE-WM groups. Conclusions: Not all patients with TLE present with cognitive impairments and alterations in the theta network were identified in TLE patients with functional cognitive deficits. Significance: The theta network may represent a sensitive measure of cognitive impairment and could predict cognitive outcomes among patients with TLE.

SUBMITTER: Pan L 

PROVIDER: S-EPMC8766724 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

altmetric image

Publications

Alterations in Neural Networks During Working Memory Encoding Related to Cognitive Impairment in Temporal Lobe Epilepsy.

Pan Liping L   Wu Yakun Y   Bao Jie J   Guo Dandan D   Zhang Xin X   Wang Jiajing J   Deng Meili M   Yu Peiran P   Wei Gaoxu G   Zhang Lulin L   Qin Xiao X   Song Yijun Y  

Frontiers in human neuroscience 20220105


<b>Objective:</b> The aim of the current study was to investigate the alterations in the neural networks of patients with temporal lobe epilepsy (TLE) during working memory (WM) encoding. <b>Methods:</b> Patients with TLE (<i>n</i> = 52) and healthy volunteers (<i>n</i> = 35) completed a WM task, during which 34-channel electroencephalogram signals were recorded. The neural networks during WM encoding were calculated in TLE patients with (TLE-WM) and without (TLE-N) WM deficits. <b>Results:</b>  ...[more]

Similar Datasets

| S-EPMC3777779 | biostudies-literature
| S-EPMC4315807 | biostudies-literature
| S-EPMC3259857 | biostudies-literature
| S-EPMC9976988 | biostudies-literature
| S-EPMC11775331 | biostudies-literature
| S-EPMC10631792 | biostudies-literature
| S-EPMC8692669 | biostudies-literature
| S-EPMC10723230 | biostudies-literature
| S-EPMC6584028 | biostudies-literature
| S-EPMC8525612 | biostudies-literature