The Effects of Prostaglandin E₂ Treatment on the Secretory Function of Mare Corpus Luteum Depends on the Site of Application: An in vivo Study.

ABSTRACT: We examined the effect of prostaglandin (PG) E₂ on the secretory function of equine corpus luteum (CL), according to the application site: intra-CL injection vs. an intrauterine (intra-U) administration. Moreover, the effect of intra-CL injection vs. intra-U administration of both luteotropic factors: PGE₂ and human chorionic gonadotropin (hCG) as a positive control, on CL function was additionally compared. Mares were assigned to the groups (n = 6 per group): (1) an intra-CL saline injection (control); (2) an intra-CL injection of PGE₂ (5 mg/ml); (3) an intra-CL injection of hCG (1,500 IU/ml); (4) an intra-U saline administration (control); (5) an intra-U administration of PGE₂ (5 mg/5 ml); (6) an intra-U administration of hCG (1,500 IU/5

SUBMITTER: Piotrowska-Tomala KK 

PROVIDER: S-EPMC8885592 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature