Simultaneous T₁ -weighted and T₂ -weighted 3D MRI using RF phase-modulated gradient echo imaging.

ABSTRACT:

Purpose

T₁ -weighted and T₂ -weighted (T1w and T2w) imaging are essential sequences in routine clinical practice to detect and characterize a wide variety of pathologies. Many approaches have been proposed to obtain T1w and T2w contrast, although many challenges still remain, including long acquisition time and limitations that favor 2D imaging. In this study, we propose a novel method for simultaneous T1w and T2w imaging using RF phase-modulated 3D gradient-echo imaging.

Theory

Configuration theory is used to derive closed-form equations for the steady state of RF phase-modulated gradient-echo signal. These equations suggest the use of small RF phase increments to provide orthogonal signal contrast with T2w and T1w in the real and imaginary components,

SUBMITTER: Tamada D 

PROVIDER: S-EPMC9006307 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature