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ABSTRACT: Objectives
To (1) determine if items on the Cognitive and Linguistic Scale (CALS) follow a Rasch distribution and (2) explore the relationship between Rasch-derived Cognitive Ability Estimates and outcome trajectory parameters using a nonlinear mixed-effects modeling approach.Design
Retrospective study.Setting
Pediatric inpatient rehabilitation hospital.Participants
A total of 252 children (N=252) aged of 2-21 years (median, 11.8 [IQR, 6.4-15.9] years) consecutively admitted to an inpatient rehabilitation brain injury unit (2008-2014) for a first inpatient admission after acquired brain injury.Interventions
Not applicable.Main outcome measures
Rasch-derived Cognitive Ability Estimates from the CALS and associated outcome trajectory parameters.Results
The CALS demonstrates adequate interval-scale properties with removal of scores from the arousal and responsivity items. Rasch-derived Cognitive Ability Estimates were associated with age (β=0.025, P<.001) such that older age was associated with a faster rate of recovery and more complete ultimate recovery. Slower recovery initiation was associated with a less complete overall cognitive recovery (Spearman ρ=-0.31; P<.001).Conclusions
The Cognitive Ability Estimates derived from the CALS and associated outcome parameters (eg, rate of recovery) may serve as an ideal outcome measure for clinical trials evaluating interventions for acquired brain injury in a pediatric rehabilitation setting.
SUBMITTER: Svingos AM
PROVIDER: S-EPMC9054937 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Svingos Adrian M AM Suskauer Stacy J SJ Slomine Beth S BS Chen Hsuan Wei HW Ellis-Stockley Michael E ME Forsyth Rob J RJ
Archives of physical medicine and rehabilitation 20211030 5
<h4>Objectives</h4>To (1) determine if items on the Cognitive and Linguistic Scale (CALS) follow a Rasch distribution and (2) explore the relationship between Rasch-derived Cognitive Ability Estimates and outcome trajectory parameters using a nonlinear mixed-effects modeling approach.<h4>Design</h4>Retrospective study.<h4>Setting</h4>Pediatric inpatient rehabilitation hospital.<h4>Participants</h4>A total of 252 children (N=252) aged of 2-21 years (median, 11.8 [IQR, 6.4-15.9] years) consecutive ...[more]