A novel highly fluorescent S, N, O co-doped carbon dots for biosensing and bioimaging of copper ions in live cells.

ABSTRACT: In this study, novel highly fluorescent sulfur, nitrogen, and oxygen co-doped carbon dots (S, N, O-CDs) were prepared from m-phenylenediamine and sulfamide by using the hydrothermal method. The prepared S, N, O-CDs show high doping rate and fluorescence yield as well as long-term fluorescence stability. In addition, S, N, O-CDs show good fluorescence response towards Cu²⁺ over a concentration range of 2-60 μM with a detection limit of 0.29 μM. Taking advantages of the properties of S, N, O-CDs including high selectivity and low cytotoxicity, S, N, O-CDs were successfully applied for Cu²⁺ sensing and imaging in the cells and O₂˙^--induced Cu²⁺ increase in the cells was observed. Furthermore, on account of strong complexation betwe

SUBMITTER: Dai Y 

PROVIDER: S-EPMC9092139 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature