Development of High-Intensity Focused Ultrasound Therapy for Inferior Turbinate Hypertrophy.

ABSTRACT:

Objectives

Inferior turbinate (IT) hypertrophy is the main cause of chronic nasal obstruction. We developed a high-intensity focused ultrasound (HIFU) ablation device to treat patients with IT hypertrophy.

Methods

First, computed tomography images of patients with no evidence of sinonasal disease were evaluated to measure and compare the IT, medial mucosal thickness (MT), and space between the nasal septum and IT according to clinical characteristics such as septal deviation. A HIFU prototype was developed based on the above human anatomical studies. The experimental study was performed in five pigs; the nasal volume and histological changes at 1 and 4 weeks postoperatively were evaluated to compare the efficacy of HIFU turbinoplasty with that of radiofrequency turbinoplasty

SUBMITTER: Kim JK 

PROVIDER: S-EPMC9149228 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature