Serum antioxidant vitamins and respiratory morbidity and mortality: a pooled analysis.

ABSTRACT:

Background

Oxidative stress plays a key role in the pathogenesis of respiratory diseases; however, studies on antioxidant vitamins and respiratory outcomes have been conflicting. We evaluated whether lower serum levels of vitamins A, C, D, and E are associated with respiratory morbidity and mortality in the U.S. adult population.

Methods

We conducted a pooled analysis of data from the 1988-1994 and 1999-2006 National Health and Nutrition Examination Survey (participants aged ≥ 20 years). We estimated covariate-adjusted odds ratios (aOR) per interquartile decrease in each serum vitamin level to quantify associations with respiratory morbidity, and covariate-adjusted hazard ratios (aHR) to quantify associations with respiratory mortality assessed prospectively through 2015. Vi

SUBMITTER: Salo PM 

PROVIDER: S-EPMC9178544 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature