Effect of single ventricular premature contractions on response to cardiac resynchronization therapy.

ABSTRACT:

Background

We lack data on the effect of single premature ventricular contractions (PVCs) on the clinical and echocardiographic response after cardiac resynchronization therapy (CRT) device implantation. We aimed to assess the predictive value of PVCs at early, 1 month-follow up on echocardiographic response and all-cause mortality.

Methods

In our prospective, single-center study, 125 heart failure patients underwent CRT implantation based on the current guidelines. Echocardiographic reverse remodeling was defined as a ≥ 15% improvement in left ventricular ejection fraction (LVEF), end-systolic volume (LVESV), or left atrial volume (LAV) measured 6 months after CRT implantation. All-cause mortality was investigated by Wilcoxon analysis.

Results

The median number of PV

SUBMITTER: Merkel ED 

PROVIDER: S-EPMC9233778 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature