Multi-CSAR: a web server for scaffolding contigs using multiple reference genomes.

ABSTRACT: Multi-CSAR is a web server that can efficiently and more accurately order and orient the contigs in the assembly of a target genome into larger scaffolds based on multiple reference genomes. Given a target genome and multiple reference genomes, Multi-CSAR first identifies sequence markers shared between the target genome and each reference genome, then utilizes these sequence markers to compute a scaffold for the target genome based on each single reference genome, and finally combines all the single reference-derived scaffolds into a multiple reference-derived scaffold. To run Multi-CSAR, the users need to upload a target genome to be scaffolded and one or more reference genomes in multi-FASTA format. The users can also choose to use the 'weighting scheme of reference genomes' for Multi-C

SUBMITTER: Liu SC 

PROVIDER: S-EPMC9252826 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature