Tuberculosis in children with severe acute malnutrition.
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ABSTRACT: Introduction
With growing attention globally to the childhood tuberculosis epidemic after decades of neglect, and with the burden of severe acute malnutrition (SAM) remaining unacceptably high worldwide, the collision of these two diseases is an important focus for improving child health.Areas covered
This review describes the clinical and public health implications of the interplay between tuberculosis and SAM, particularly for children under the age of five, and identifies priority areas for improved programmatic implementation and future research. We reviewed the literature on PubMed and other evidence known to the authors published until August 2021 relevant to this topic.Expert opinion
To achieve the World Health Organization's goal of eliminating deaths from childhood tuberculosis and to improve the abysmal outcomes for children with SAM, further research is needed to 1) better understand the epidemiologic connections between child tuberculosis and SAM, 2) improve case finding of tuberculosis in children with SAM, 3) assess unique treatment considerations for tuberculosis when children also have SAM, and 4) ensure tuberculosis and SAM are strongly addressed in decentralized, integrated models of providing primary healthcare to children.
SUBMITTER: Vonasek BJ
PROVIDER: S-EPMC9280657 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Publications
Tuberculosis in children with severe acute malnutrition.
Vonasek Bryan J BJ Radtke Kendra K KK Vaz Paula P Buck W Chris WC Chabala Chishala C McCollum Eric D ED Marcy Olivier O Fitzgerald Elizabeth E Kondwani Alexander A Garcia-Prats Anthony J AJ
Expert review of respiratory medicine 20220228 3
<h4>Introduction</h4>With growing attention globally to the childhood tuberculosis epidemic after decades of neglect, and with the burden of severe acute malnutrition (SAM) remaining unacceptably high worldwide, the collision of these two diseases is an important focus for improving child health.<h4>Areas covered</h4>This review describes the clinical and public health implications of the interplay between tuberculosis and SAM, particularly for children under the age of five, and identifies prio ...[more]
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