Colorimetric assay based on NiCo₂S₄@N,S-rGO nanozyme for sensitive detection of H₂O₂ and glucose in serum and urine samples.

ABSTRACT: Traditional bimetallic sulfide-based nanomaterials often have a small specific surface area (SSA), low dispersion, and poor conductivity, thereby limiting their wide applications in the nanozyme-catalytic field. To address the above issues, we herein integrated NiCo₂S₄ with N,S-rGO to fabricate a nanocomposite (NiCo₂S₄@N,S-rGO), which showed a stronger peroxidase-mimetic activity than its pristine components. The SSA (155.8 m² g^-1) of NiCo₂S₄@N,S-rGO increased by ∼2-fold compared to NiCo₂S₄ with a pore size of 7-9 nm, thus providing more active sites and charge transfer channels. Based on the Michaelis-Menten equation, the affinity of this nanocomposite increased 40% and 1.1∼10.6-f

SUBMITTER: Ye H 

PROVIDER: S-EPMC9295685 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature