Causes of cardiovascular and noncardiovascular death in the ISCHEMIA trial.

ABSTRACT:

Background

The International Study of Comparative Health Effectiveness with Medical and Invasive Approaches trial demonstrated no overall difference in the composite primary endpoint and the secondary endpoints of cardiovascular (CV) death/myocardial infarction or all-cause mortality between an initial invasive or conservative strategy among participants with chronic coronary disease and moderate or severe myocardial ischemia. Detailed cause-specific death analyses have not been reported.

Methods

We compared overall and cause-specific death rates by treatment group using Cox models with adjustment for pre-specified baseline covariates. Cause of death was adjudicated by an independent Clinical Events Committee as CV, non-CV, and undetermined. We evaluated the association of r

SUBMITTER: Sidhu MS 

PROVIDER: S-EPMC9310436 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature