Ontology highlight
ABSTRACT: Purpose
To describe demographic and clinical characteristics of chronic obstructive pulmonary disease patients managed in US primary care.Methods
This was an observational registry study using data from the Chronic Obstructive Pulmonary Disease (COPD) Optimum Patient Care DARTNet Research Database from which the Advancing the Patient Experience COPD registry is derived. Registry patients were aged ≥35 years at diagnosis. Electronic health record data were collected from both registries, supplemented with patient-reported information/outcomes from the Advancing the Patient Experience registry from 5 primary care groups in Texas, Ohio, Colorado, New York, and North Carolina (June 2019 through November 2020).Results
Of 17,192 patients included, 1,354 were also in the Advancing the Patient Experience registry. Patients were predominantly female (56%; 9,689/17,192), White (64%; 9,732/15,225), current/ex-smokers (80%; 13,784/17,192), and overweight/obese (69%; 11,628/16,849). The most commonly prescribed maintenance treatments were inhaled corticosteroid with a long-acting β2-agonist (30%) and inhaled corticosteroid with a long-acting muscarinic antagonist (27%). Although 3% (565/17,192) of patitents were untreated, 9% (1,587/17,192) were on short-acting bronchodilator monotherapy, and 4% (756/17,192) were on inhaled corticosteroid monotherapy. Despite treatment, 38% (6,579/17,192) of patients experienced 1 or more exacerbations in the last 12 months. These findings were mirrored in the Advancing Patient Experience registry with many patients reporting high or very high impact of disease on their health (43%; 580/1,322), a breathlessness score 2 or more (45%; 588/1,315), and 1 or more exacerbation in the last 12 months (50%; 646/1,294).Conclusions
Our findings highlight the high exacerbation, symptom, and treatment burdens experienced by COPD patients managed in US primary care, and the need for more real-life effectiveness trials to support decision making at the primary care level.
SUBMITTER: Pace WD
PROVIDER: S-EPMC9328699 | biostudies-literature | 2022 Jul-Aug
REPOSITORIES: biostudies-literature
Pace Wilson D WD Brandt Elias E Carter Victoria A VA Chang Ku-Lang KL Edwards Chelsea L CL Evans Alexander A Fox Chester C Gaona Gabriela G Han MeiLan K MK Kaplan Alan G AG Kent Rachel R Kocks Janwillem W H JWH Kruszyk Maja M Le Lievre Chantal E CE Li Voti Tessa T Mahle Cathy C Make Barry B Ratigan Amanda R AR Shaikh Asif A Skolnik Neil N Stanley Brooklyn B Yawn Barbara P BP Price David B DB
Annals of family medicine 20220701 4
<h4>Purpose</h4>To describe demographic and clinical characteristics of chronic obstructive pulmonary disease patients managed in US primary care.<h4>Methods</h4>This was an observational registry study using data from the Chronic Obstructive Pulmonary Disease (COPD) Optimum Patient Care DARTNet Research Database from which the Advancing the Patient Experience COPD registry is derived. Registry patients were aged ≥35 years at diagnosis. Electronic health record data were collected from both regi ...[more]