Intrauterine interventions for women with two or more implantation failures: A systematic review and network meta-analysis.

ABSTRACT:

Objective

To compare the effectiveness of different intrauterine interventions for women with two or more unexplained implantation failures.

Design

A systematic review and network meta-analysis of randomized controlled trials (RCTs).

Patients

Women with two or more implantation failures undergoing fresh or frozen embryo transfer (ET).

Interventions

An electronic search of the following databases: Pubmed, Cochrane Central Register of Controlled Trials (CENTRAL), and Embase.

Main outcome measures

Clinical pregnancy, live birth/ongoing pregnancy, and miscarriage.

Results

We included 21 RCTs(3079 women) in the network meta-analysis. The network meta-analysis showed that compared with control treatment, platelet-rich plasma(PRP), peripheral blood monon

SUBMITTER: Jin XH 

PROVIDER: S-EPMC9464901 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature