Sordaria macrospora Sterile Mutant pro34 Is Impaired in Respiratory Complex I Assembly.

ABSTRACT: The formation of fruiting bodies is a highly regulated process that requires the coordinated formation of different cell types. By analyzing developmental mutants, many developmental factors have already been identified. Yet, a complete understanding of fruiting body formation is still lacking. In this study, we analyzed developmental mutant pro34 of the filamentous ascomycete Sordaria macrospora. Genome sequencing revealed a deletion in the pro34 gene encoding a putative mitochondrial complex I assembly factor homologous to Neurospora crassa CIA84. We show that PRO34 is required for fast vegetative growth, fruiting body and ascospore formation. The pro34 transcript undergoes adenosine to inosine editing, a process correlated with sexual development in fruiting

SUBMITTER: Hamann A 

PROVIDER: S-EPMC9605262 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature