Ontology highlight
ABSTRACT:
SUBMITTER: De Paepe B
PROVIDER: S-EPMC9654287 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20221029 21
Growth differentiation factor 15 (GDF-15) is a stress-induced transforming growth factor-β superfamily cytokine with versatile functions in human health. Elevated GDF-15 blood levels associate with multiple pathological conditions, and are currently extensively explored for diagnosis, and as a means to monitor disease progression and evaluate therapeutic responses. This review analyzes GDF-15 in human conditions specifically focusing on its association with muscle manifestations of sarcopenia, m ...[more]