Post-traumatic endophthalmitis prophylaxis: a systematic review and meta-analysis.

ABSTRACT:

Purpose

The goal of this study is to determine if certain aspects of endophthalmitis prophylaxis strategies are superior to others.

Design

This investigation is a systematic review and meta-analysis.

Methods

All studies specifying a type of prophylaxis strategy and resulting rates of endophthalmitis were included. Time course, method of administration, and antibiotic regimen, and confounding factors were collected and included for meta-regression.

Results

Time courses greater than 24 h did not significantly improve outcomes. Likewise, intraocular and/or intravenous antibiotic administration methods did not significantly outperform oral administration. No antibiotic regimens performed differently from vancomycin/ ≥ 3^rd generation cephalosporin except

SUBMITTER: Van Swol JM 

PROVIDER: S-EPMC9672185 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature