The longitudinal course of pediatric acute respiratory distress syndrome and its time to resolution: A prospective observational study.

ABSTRACT:

Background

The longitudinal course of patients with pediatric acute respiratory distress syndrome (PARDS) is not well described. In this study, we describe the oxygenation index (OI) and oxygen saturation index (OSI) in mild, moderate, and severe PARDS over 28 days and provide pilot data for the time to resolution of PARDS (T _res), as a short-term respiratory-specific outcome, hypothesizing that it is associated with the severity of PARDS and clinical outcomes.

Methods

This prospective observational study recruited consecutive patients with PARDS. OI and OSI were trended daily over 28 days. T _res (defined as OI < 4 or OSI < 5.3 on 2 consecutive days) were described based on PARDS severity and analyzed with Poisson and logistic regression t

SUBMITTER: Wong JJM 

PROVIDER: S-EPMC9723458 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature