Impact of the fluid challenge infusion rate on cardiac stroke volume during major spinal neurosurgery: a prospective single center randomized interventional trial.

ABSTRACT:

Background

Fluid therapy, including the choice of a crystalloid or colloid infusion, the execution time of a volume bolus, and the expected volume need of a patient during surgery, varies greatly in clinical practice. Different goal directed fluid protocols have been developed, where fluid boluses guided by dynamic preload parameters are administered within a specific period.

Objective

To study the efficacy of two fluid bolus infusion rates measured by the response of hemodynamic parameters.

Design

Monocentric randomized controlled interventional trial.

Setting

University hospital.

Patients

Forty patients undergoing elective major spinal neurosurgery in prone position were enrolled, thirty-one were finally analyzed.

Interventions

Patients were ran

SUBMITTER: Schmidt G 

PROVIDER: S-EPMC9783430 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature