Characterization of the fatty acid metabolism-related genes in lung adenocarcinoma to guide clinical therapy.

ABSTRACT:

Background

Lung adenocarcinoma (LUAD) is a common cancer with a bad prognosis. Numerous investigations have indicated that the metabolism of fatty acids plays an important role in the occurrence, progression, and treatment of cancer. Consequently, the objective of the current investigation was to elucidate the role and prognostic significance of genes associated with fatty acid metabolism in patients diagnosed with LUAD.

Materials and methods

The data files were acquired from The Cancer Genome Atlas database and GSE31210 dataset. Univariate Cox and least absolute shrinkage and selection operator regression analyses were conducted to establish a prognostic risk scoring model depending on fatty acid metabolism-associated genes to predict the prognosis of patients with LUAD. pR

SUBMITTER: Huang G 

PROVIDER: S-EPMC9784226 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature