Genetic variation rs1121980 in the fat mass and obesity-associated gene (FTO) is associated with dietary intake in Koreans.

ABSTRACT:

Background

Fat mass and obesity-associated gene (FTO) is a well-known gene associated with body weight and obesity risk. Recent studies have suggested that genetic variations in FTO may play a role in the regulation of food preference and consumption. However, little is known with respect to Asian populations.

Objective

This study examined whether rs1121980 C > T in FTO is associated with food intake in Koreans.

Design

This study was performed using data from the Korean Genome and Epidemiology Study (Ansan/Ansung cohort). Dietary intake was determined using the semi-food frequency questionnaire, and the FTO rs1121980 genotypes of 6,262 individuals (3,049 males and 3,213 females) were analyzed along with sex and body mass index (BMI).

Res

SUBMITTER: Goh Y 

PROVIDER: S-EPMC9793768 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature