Purine Intake and All-Cause Mortality in Ovarian Cancer: Results from a Prospective Cohort Study.

ABSTRACT:

Background

Current biological evidence suggests that purine involvement in purine metabolism may contribute to the development and progression of ovarian cancer (OC), but the epidemiological association is currently unknown.

Methods

A total of 703 newly diagnosed patients with OC aged 18-79 years were included in this prospective cohort study. Utilizing a verified food-frequency questionnaire, the participants' dietary consumption was gathered. Using medical records and ongoing follow-up, the deaths up until 31 March 2021 were determined. To assess the hazard ratios (HRs) and 95% confidence intervals (CIs) of purine intake with OC mortality, Cox proportional-hazard models were utilized.

Results

During the median follow-up of 31 months (interquartile: 20-47 months), 13

SUBMITTER: Du Z 

PROVIDER: S-EPMC9965699 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature