Alterations in the immune system persist after one year of convalescence in severe COVID-19 patients.

ABSTRACT:

Introduction

Severe COVID-19 originates a myriad of alterations in the immune system during active disease, especially in the T and NK cell compartments, but several studies in the last year have unveiled some alterations that persist in convalescence. Although most of the studies follow the participants for a short recovery time, studies following patients up to three or six months still find alterations. We aimed at evaluating changes in the NK, T and B cell compartments after severe COVID-19 in participants with a median recovery time of eleven months.

Methods

Eighteen convalescent of severe COVID-19 (CSC), 14 convalescent of mild COVID-19 (CMC) and nine controls were recruited. NKG2A, NKG2C, NKG2D and the activating receptor NKp44 were evaluated in NK^bright, N

SUBMITTER: Abarca-Zabalia J 

PROVIDER: S-EPMC9969554 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature