Project description:Advances in the understanding of cancer cell biology and response to drug treatment have benefited from new molecular technologies and methods for integrating information from multiple sources. The NCI-60, a panel of 60 diverse human cancer cell lines, has been used by the National Cancer Institute to screen >100,000 chemical compounds and natural product extracts for anticancer activity. The NCI-60 has also been profiled for mRNA and protein expression, mutational status, chromosomal aberrations, and DNA copy number, generating an unparalleled public resource for integrated chemogenomic studies. Recently, microRNAs have been shown to target particular sets of mRNAs, thereby preventing translation or accelerating mRNA turnover. To complement the existing NCI-60 datasets, we have measured expression levels of microRNAs in the NCI-60.

2007-04-02 | E-MEXP-1029 | biostudies-arrayexpress

Agilent-013282 array CGH on NCI-60 cancer cell lines

Project description:The NCI-60 cancer cell lines have been used for studying cancer pathogenesis and for drug discovery. This dataset adds to the growing number of datasets on various genomic platforms that have been made public on Cellminer (http://discover.nci.nih.gov/cellminer/)

2013-10-31 | GSE48568 | GEO

Nimblegen 385K array CGH on NCI-60 cancer cell lines

2011-10-24 | GSE30291 | GEO

Illumina Human1Mv1_C array CGH on NCI-60 cancer cell lines

2013-10-31 | GSE47620 | GEO