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Patient Blood Management improves outcome in oncologic surgery.


ABSTRACT: Patient Blood Management (PBM) is a systematic quality improving clinical model to reduce anemia and avoid transfusions in all kinds of clinical settings. Here, we investigated the potential of PBM in oncologic surgery and hypothesized that PBM improves 2-year overall survival (OS).Retrospective analysis of patients 2 years before and after PBM implementation. The primary endpoint was OS at 2 years after surgery. We identified a sample size of 824 to detect a 10% improvement in survival in the PBM group.The analysis comprised of 836 patients that underwent oncologic surgery, 389 before and 447 after PBM, was implemented. Patients in the PBM+ presented significantly more frequent with normal hemoglobin values before surgery than PBM- (56.6 vs. 35.7%; p??12 g/dl in female and >?13 g/dl in male) before surgery (HR 0.43, 95% CI 0.29-0.65, p?

SUBMITTER: Keding V 

PROVIDER: S-EPMC6081799 | biostudies-other | 2018 Aug

REPOSITORIES: biostudies-other

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Patient Blood Management improves outcome in oncologic surgery.

Keding Vivienne V   Zacharowski Kai K   Bechstein Wolf O WO   Meybohm Patrick P   Schnitzbauer Andreas A AA  

World journal of surgical oncology 20180807 1


<h4>Background</h4>Patient Blood Management (PBM) is a systematic quality improving clinical model to reduce anemia and avoid transfusions in all kinds of clinical settings. Here, we investigated the potential of PBM in oncologic surgery and hypothesized that PBM improves 2-year overall survival (OS).<h4>Methods</h4>Retrospective analysis of patients 2 years before and after PBM implementation. The primary endpoint was OS at 2 years after surgery. We identified a sample size of 824 to detect a 1  ...[more]

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