ChIP-seq analysis of androgen receptor binding in epididymis of ArKI mice

ABSTRACT: To analyze how SUMOylation of AR affects its chromatin binding, we generated a mouse model (ArKI) in which the two conserved SUMO acceptor lysines of androgen receptor (AR) were permanently abolished by converting them to arginines (ArK381R, K500R). ChIP-seq was used to analyse how the lack of AR SUMOylation affects the chromatin binding of AR in epididymis.

ORGANISM(S): Mus musculus

PROVIDER: GSE121151 | GEO | 2019/01/09

REPOSITORIES: GEO