Phenylacetaldehyde inhibits development of colorectal cancer

ABSTRACT: Phenylacetaldehyde (PAA), a product of phenylalanine metabolism, is catabolized by microbiota and has demonstrated anticancer properties in breast cancer. As intestinal homeostasis is influenced by gut microbiome, we investigated the effect of PAA on colorectal cancer (CRC). In the study, we interrogated the mechanistic pathways induced by PAA treatment using RNA sequencing.

ORGANISM(S): Homo sapiens

PROVIDER: GSE207618 | GEO | 2023/07/11

REPOSITORIES: GEO